The Omicrons aren't actually that dead at the minute, Core and Order are clashing fairly often with both faction and indie intervention. However that is only 1 or 2 systems.
Omega's are dead 'cause Hessians and Corsairs are almost non-existent though you'll find miners from various factions down there fairly often. There isn't any particular hotspots at the moment really though Rheinland and Liberty have kinda started attacking each other again and GRN/BAF skirmishes look to be on the up.
Aside from that there's no real hot spots apart from typical New York scumbaggery.