So I don't play this game anymore but I do look at story beats from time to time to see if there's anything worth returning to.
One event that I remember when I found worthwhile to open up Discovery again was the addition of Earhart. It seemed interesting, and it promised further story development after it was added as a basically space black hole dumping ground. There were a few events, some battles, Starfliers still poast holes and so on...
But did anything actually happen lore-wise with it? Was it explained why jump gates shut down for a few hours? Did this go anywhere or are there still any plans to make the story of that system more interesting?
The Blackout happened directly due to an event known as the "Pulse", which was a subspace explosion originating in Earhart. In-universe, however, the laymen usually associate it with the explosion of the Dublin JG. Earhart is basically a subspace nexus and also the destination of all ships that presumably "disappeared" due to jump malfunction.
There's a lot of speculation about the trigger that caused the pulse, considering that Kusari had in the same timeframe began to develop their own jump drive system with the Niyodo.
More recently, we have the Deep Omegas, basically a dangerous, mostly-uncharted region of the Omegas teeming with hostile patrols and treasures. No relation to any subspace anomaly.
