I would think that Lane Hackers would be viewed as "subject to purification," as they use Cardimine to enhance intelligence beyond standard human capabilities. That could be viewed as unforgivable, since to me there feels to be a religiously zealous theme going on here.
I assume you don't list some factions due to the primary ZoI lacking Liberty, Kusari and Rheinland, however Lane Hackers can operate in Manchester, so there's that low chance you might come across one or two.
Edit: Dang, hivemind moment. Took me a while to type this post, ninja'd on the Lane Hacker sentiment.
