Combining NPCs and players is an awful idea for PvP right now - NPCs are too disturbing. I'd much rather see player characters invested in the conflict and their factions than nameless and clueless NPCs.
I believe that something could be suitable for this system as it's literally the bloodiest conflict among unlawful factions in Sirius if my memory is correct.
The Hammen Hole is by far big enough to support both, really. Looking at the relatively small bubbles in Munich, Lorraine, Coronado and Vespucci, a similarly small bubble can easily be placed in there, potentially slightly above or below the plane. The exclusion zone alone is an ellipsoid of 28.000 x 14.000 x 13.000. Right now in the very center of it is an NPC spawn with assault and gunboat groups. That bubble can easily moved to the upper or lower edge of the exclusion zone and have cruisers and battleships be added to it and it wouldn't annoy anyone - simply because the Hammen Hole is definitely big.