Yes, but once again - the whole point of smuggling is to get your cargo to it's destination without being stopped, caught, or destroyed. Trying to do so in a very large, very obvious ship - or a ship with little to no defenses (like the whale) - directly conflicts with the way smugglers tend to do things.
Semi-large ships (like the borderworlds transport, firefly, pirate transport, etc.) are used to bring cardamine from the borderworlds into liberty space - generally to buffalo base. From there, Rogues make a run across the system to get the cardamine to Rochester, and from Rochester the Junkers use CSV's and civilian ships to move small amounts of cardamine to manhattan and the orbiting stations where the populace buys it illegally.
People trying to run an advanced train that has little to no armor or shielding, carrying 5000 units of cardamine, directly to manhattan's mooring fixture are incredibly OORP for smugglers. Not only is their ship, in-RP, not in any way suited for the job of smuggling through dangerous areas (smugglers have to deal with lawfuls, pirates, and environmental hazards - all of which where a small, manuverable ship that can escape more easily is preferred), they're also taking their cargo to a place they shouldnt be.
I fly a firefly, it's a perfect ship for smuggling - fairly agile, can get through debris and asteroid fields easily, has the armor to withstand radiation areas, has enough firepower to defend itself against the odd patrol or pirate, and has moderate cargo space - and I still never try to take cardamine or artifacts or any other contraband directly to a lawful base if any lawfuls are around. Cardamine and artifacts should always be going to rochester or beaumont, not to manhattan.
Hell I havent even been in liberty lately with all the crap going on there, I've found a couple extremely profitable smuggling routes in the borderworlds that are much safer than trying to take anything into liberty.