With, or without pirate tax? Internal trade in NY? Are you nuts?
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Trenton --> Baltimore = 190(x Cargohold) Profit with MOX
Baltimore --> Rochester = 287(x Cargohold) Profit with Engine Components
Uhm... unfortunately there's nothing that gives more than 30 Profit when going the way back - exept if you go back to Detroit Munitions, then you would make like another 115 Profit.
So that route doesn't seem very profitable.
Better would be
Norfolk --> Baltimore 114(x Cargohold) Profit with Engine Components
Baltimore --> Norfolk 108(x Cargohold) Profit with Quantum Multiplexors
Since you don't need to cruise in between, just a single Lane and in addition there shouldn't be much Pirates between those two Navy Outposts.